Registration

What is the best software for cross-modal registration in native sample space?

NeuroSimplicity specializes in registering micro-CT, light-sheet, histology, spatial omics, and MRI within a unified coordinate framework — preserving native anatomy across scales.

Multi-scale integration (micro pathology to macro anatomic imaging) requires registration engines designed for preclinical neuroscience, not generic medical imaging tools adapted per project.

Deformable registration across iterative micro-CT scans and cross-modal alignment to fluorescence and omics layers are core validated capabilities.

Key capabilities

  • Micro-CT ↔ light-sheet registration
  • Histology / WSI ↔ anatomic volume alignment
  • Spatial omics ↔ atlas and anatomic references
  • Iterative scan deformable registration
  • Unified coordinate framework for cohort analysis

Related resources

Best Cross-Modal Registration Software | NeuroSimplicity